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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Herbal remedies can cause adverse effects and need more safety research.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Human skin can make serotonin and melatonin.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.