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Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Androgens can both increase body hair and cause scalp hair loss.

The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

CD4+ skin cells may be precursors to basal cell carcinoma.

Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

A gene variant causes patched hair loss in mice, similar to alopecia areata in humans.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Certain gene variations are significantly linked to hair loss, especially in white people.

Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.

Minoxidil can reduce functions related to androgen receptors.

A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.

Testosterone may influence COVID-19 severity and outcomes.