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This study developed a novel smart deoxyribozyme-based fluorescent sensor that efficiently detects androgen receptor mRNA with high selectivity and can be adapted to target various nucleic acid sequences.

In this study, researchers examined androgen receptor activity in the adult mouse brain and found specific expression in key brain areas, which could inform understanding of cognitive side effects in humans undergoing androgen deprivation therapy for prostate cancer.

In this study, Meis1 was found to regulate epidermal homeostasis and act as a proto-oncogenic factor in skin tissues, with differences in expression patterns between normal and tumor cells.

In this review, an association was reported between early-onset androgenetic alopecia and several health conditions like obesity and cardiovascular disease, with genetic and therapeutic research ongoing to improve treatment.

This study concluded that prepubertal girls with hypertrichosis have androgen receptors with enhanced sensitivity, which may contribute to their increased body hair growth.

This review discussed the variability in measuring serum testosterone levels and emphasized the need for standardizing testing and sharing updated treatment protocols to manage male hypogonadism effectively. It also highlighted the importance of considering secondary hypogonadism causes and suggested consulting with endocrinologists for optimal management.

This study found that hair steroid analysis effectively detected increased hormone levels from both a single testosterone dose and laboratory-induced stress, revealing individual context factors like relationship status also impact hair hormone concentrations.

This study found that minoxidil suppressed androgen receptor functions and stability, suggesting its potential use in treating diseases related to the androgen-AR pathway.

This study found that a novel IKZF1 mutation, p.L188V, is linked to juvenile-onset systemic lupus erythematosus and alters B-cell activation by disrupting normal DNA binding.

Androgenetic alopecia treatments focus on reducing hair loss by targeting hormones, with new therapies showing promise but needing more research.

This study found that specific genetic variants in the CYP21A2 and CYP19A1 genes were associated with severe acne vulgaris among Han Chinese, particularly in male patients.

This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.

This study reported that a new formulation of finasteride solid lipid nanoparticles, combined with LPC and NTC, enhanced hair growth in mice without visible skin reactions, suggesting it could effectively manage androgenetic alopecia.

This study suggests that myotonic dystrophies may qualify as segmental progeroid disorders due to molecular and clinical similarities with typical progeroid syndromes.

In this study, dutasteride more effectively reduced prostate cancer cell viability than finasteride in vitro, but did not significantly alter the angiogenic response.

This review discusses hirsutism in women with PCOS who present with normal androgen levels and highlights diagnostic challenges, reporting no new clinical findings.

This systematic review and meta-analysis reported potential risk variants for acne in genes related to inflammation and sebaceous gland function, including TNF, CYP17A1, and FST, across diverse populations.

This study highlights the importance of understanding the roles of hyperandrogenemia and insulin resistance in the development and progression of PCOS, emphasizing further research to clarify their mutual influence.

This review discusses the dual role of testosterone in COVID-19 progression and suggests its importance in understanding the disease's mechanisms, highlighting the need for further targeted research.

This study found that higher BMI in PCOS patients at a Chinese clinic was associated with functional disorders of androgen excess, suggesting BMI may predict hyperandrogenism in this population.

This review discusses the benefits and cardiovascular risks of androgen deprivation therapy for prostate cancer patients, noting that optimizing cardiovascular risk factors is important when using ADT.

This study found that the gene SRD5A1, associated with methylation changes due to early-life environment, may play a role in altering reproductive phenotypes in women by delaying pubertal onset and decreasing ovarian reserve.

This article discusses the potential role of probiotics and synbiotics in managing hirsutism through insulin resistance but reports no new clinical results, calling for further research.

This review explores the key factors influencing hair growth implicated in androgenetic alopecia and reports no new clinical findings.

This review discusses the structure and function of the testes in male reproduction and development, noting the complex hormonal regulation within the hypothalamic-pituitary-gonadal axis but reports no new clinical results.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Female Pattern Hair Loss affects women's quality of life, with limited treatment options and a need for more research.