research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders
Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
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research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Methotrexate in Dermatology
Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.
research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation
Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
research Niosomes as a Promising Carrier for Topical Drug Delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Telogen Effluvium: A Review of Acute and Chronic Forms
Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
research The Prevalence and Management of Side Effects of Lithium and Anticonvulsants as Mood Stabilizers in Bipolar Disorder from a Clinical Perspective
Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.
research Recent Advances in Microneedle Composites for Biomedical Applications: Advanced Drug Delivery Technologies
Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Hair Follicles as a Target Structure for Nanoparticles
Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research Investigation of Follicular and Non-Follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles
Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Acorus Calamus: A Bio-Reserve of Medicinal Values
*Acorus calamus* has many medicinal benefits but needs more safety research.
research Preparation and Characterization of Beta-Sitosterol-Loaded Nanostructured Lipid Carriers for Butter Enrichment
Researchers made a special butter with added betasitosterol that could be healthier for the heart and stayed good for three months.
research Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture
Autophagy is important for human hair growth and health.
research Analysis of Protein Interactions by Surface Plasmon Resonance
Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Update on the Dermatologic Use of Systemic Glucocorticosteroids
Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
research Novel Cosmeceuticals from Plants: An Industry-Guided Review
Plant-based ingredients are effective and safe for modern skincare products.
research Refinement of Technique in Injection Lipolysis Based on Scientific Studies and Clinical Evaluation
Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research A Primer for Studying Cell Cycle Dynamics of the Human Hair Follicle
The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
research Levetiracetam in the Treatment of Idiopathic Generalized Epilepsies
Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.
research The Diagnosis and Treatment of Hair and Scalp Diseases
Hair loss requires customized treatments based on its various causes and types.