Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers developed a method using stencils to create controlled stiffness gradients in alginate hydrogels, revealing that stiffer regions within the gels promote deeper invasion by breast cancer cells, facilitating the study of mechanosensitive cellular behaviors.

This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.

This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.

This review discusses recent developments in targeted melanoma therapies, including BRAF/MEK/ERK pathway inhibitors and challenges like resistance and skin toxicities, but reports no new clinical results.

This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.

This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.

In this study, researchers found that Elastic Net DNA methylation clocks are not accurate for distinguishing between individuals or identifying health markers, but measuring biological "noise" in stable cytosines may serve as a potential biomarker of aging and disease.

This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.

This review discusses the therapeutic potential of potassium channel openers for various conditions, but notes that their clinical role is not yet fully established.

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This review discusses the effects of photobiomodulation, particularly its potential to reduce inflammation in various conditions, but it does not report new clinical findings.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.

This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.

This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.

This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.

This review discusses recent advancements in understanding and managing congenital adrenal hyperplasia, including improvements in screening, diagnostics, and potential genetic and cell-based treatments, but reports no new clinical findings.

This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.

This review discusses the development and potential therapeutic applications of adenosine receptor agonists and positive allosteric modulators, noting that while many clinical trials have been unsuccessful, initial results for new compounds are promising.

This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.

This systematic review suggests that turmeric and curcumin products, both oral and topical, may offer therapeutic benefits for various skin conditions, though further research is necessary to evaluate efficacy more thoroughly.

This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.

This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.

This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.

This review discusses recent strategies targeting the neuroactive steroid biosynthetic pathway to enhance neurosteroidogenesis, highlighting their potential benefits for neurodegenerative and neuropsychiatric diseases, but reports no new clinical findings.

This review provides an overview of recent tissue engineering and regenerative medicine developments in Asia, highlighting significant advances, representative research achievements, and discussing future directions, without presenting new research results.

This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.

This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.