research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Not having enough cystatin M/E protein causes less hair growth and dry skin.
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research TLR3 Signaling Modulates Immunomodulatory Property of Human Periodontal Ligament Stem Cells
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
research Syndactyly Type III and Hypotrichosis in Oculodentodigital Syndrome with GJA1 Mutation
A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.
research The Role of Astrotactin2 in Regulating Mammalian Skin Polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.
research Postzygotic KRAS G12C Mutation Associated with Various Malignancies Also Underlying Epidermal Nevus Syndrome
A specific mutation known for causing cancer is also found to cause a skin condition in a young girl.
research A Novel Splice Site Mutation in LIPH Identified in a Japanese Patient with Autosomal Recessive Woolly Hair
Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
research An Immune Regulatory CCT Repeat Containing Oligodeoxynucleotide Capable of Causing Hair Loss in Male Mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research A Synonymous Polymorphism of APCDD1 Affects Translation Efficacy and Is Associated with Androgenic Alopecia
A specific gene change in APCDD1 increases the risk of hair loss.
research Preparation and Evaluation of a Multimodal Minoxidil Microemulsion Versus Minoxidil Alone in the Treatment of Androgenic Alopecia of Mixed Etiology: A Pilot Study
The multimodal microemulsion with minoxidil, diclofenac, and tea tree oil is more effective for hair growth than minoxidil alone.
research Screened and Examined: Health Benefits of Manuka Honey
Manuka honey is effective for treating wounds and burns.
research Structural Requirements of Minoxidil Analogs for Enhancing Lysyl Hydroxylase Inhibitory Activity
Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
research In This Issue
Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
research Crystal Structure and Synthesis of 3β-Benzoyloxy-4-pregnen-16α,17α-epoxy-6,20-dione
The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.
research Cosmetic Surgery of the Skin: Principles and Techniques
The book details advanced techniques in cosmetic dermatology for experienced surgeons.
research News And Announcements: 1994 AAO-HNS Research Grants, Workshops, And New Officers
Several doctors received research grants, new workshops and conferences were announced, and new officers were elected.
research The Assessment and Treatment of Older Adults
Amphetamine use may not cause hair loss, "geezer" traits are normal aging, not all educated older people are stereotypes, and metronidazole can rarely cause lung disease.
research A Systematic Study of Determination and Validation of Finasteride Impurities Using Liquid Chromatography
Method found to accurately identify finasteride impurities using liquid chromatography.
research Summary of the Recommendations on Sexual Dysfunctions in Women
The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification
The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.
research Fidelity of the Human Mitochondrial DNA Polymerase
Human mitochondrial DNA polymerase makes very few errors, crucial for preventing degenerative diseases.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations, and Applications
Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Mycorrhiza-Induced Changes in Root Growth and Nutrient Absorption of Tea Plants
AMF inoculation boosts tea plant growth and nutrient absorption.
research Cortical Cell Types and Intermediate Filament Arrangements Correlate with Fiber Curvature in Japanese Human Hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research Silk-Inspired In Situ Hydrogel with Enhanced Anti-Tumor Immunity for Photodynamic Therapy in Melanoma and Infected Wound Healing
The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.
research A Review on Citrullus Colocynthis Schrad.: From Traditional Iranian Medicine to Modern Phytotherapy
Citrullus colocynthis has pain-relieving, anti-inflammatory, antidiabetic, and hair growth benefits, but can cause side effects like colic and diarrhea.
research The Prevalence of Metabolic Disorders in Various Phenotypes of Polycystic Ovary Syndrome: A Community-Based Study in Southwest Iran
Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.