November 2007 in “Cancer Epidemiology and Prevention Biomarkers” In this study, PSA levels were significantly lower among African-American men with higher C-peptide levels and Caucasian men with higher HbA1c levels, suggesting a link between metabolic markers and prostate cancer detection.
March 2013 in “Journal of pediatric nursing” This case report presents a 14-year-old girl with type A insulin resistance, illustrating diagnostic processes to differentiate it from type 2 diabetes in the context of pediatric obesity and hyperglycemia.
2 citations
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April 2023 in “Diabetes Metabolic Syndrome and Obesity” 2h-ICPR can help screen for insulin antibodies in type 2 diabetes patients.
1 citations
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January 2014 in “mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)” This study found that women with PCOS had higher glucose and C-peptide levels but similar insulin levels compared to a control group.
This study introduced Cadd4, a peptide-based degrader developed using computer-aided drug design, which effectively reduced PCSK9 levels and increased LDL receptor expression, resulting in decreased plasma cholesterol and LDL-C levels in hypercholesterolemic mice, without liver toxicity.
18 citations
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August 2012 in “Cutaneous and Ocular Toxicology” This study found that alopecia areata patients had increased insulin resistance compared to controls, suggesting a potential link between inflammation, stress axis activation, and insulin resistance in this population.
January 2024 in “International Journal of Dermatology Research” This study reported a significant association between insulin resistance and acne vulgaris, with a higher prevalence of insulin resistance observed among acne patients compared to healthy controls.
42 citations
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September 2007 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.
4 citations
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November 2022 in “Acta dermato-venereologica” This study found that patients with hidradenitis suppurativa had lower trabecular bone score and total hip bone mineral density compared to controls, with a high prevalence of vitamin D deficiency.
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
2 citations
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December 2010 in “Zhonghua neifenmi daixie zazhi” This study found that autologous nonmyeloablative hematopoietic stem cell transplantation may help some newly-onset type 1 diabetes patients become insulin-free, although gastrointestinal and other mild side effects were observed.
37 citations
,
March 2006 in “Regulatory Peptides” This study reports that GLP-1 receptors and proglucagon are expressed in the skin of newborn mice, with GLP-1 potentially playing a role in skin development and hair follicle formation.
February 2020 in “Benha Journal of Applied Sciences” This study suggests that high nesfatin-1 levels and insulin resistance are linked to an increased risk and severity of acne vulgaris.
114 citations
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October 2009 in “Gastroenterology” This review discusses zinc's role as an essential trace element in human nutrition, particularly its importance in total parenteral nutrition, and reports no new clinical results.
8 citations
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July 2022 in “Frontiers in plant science” This review outlines the current understanding of how pH contributes to root hair development and reports no new experimental findings.
This review discusses potential cosmeceutical treatments for hair loss, including ingredients like procyanidins and isoflavones, but does not present new clinical outcomes; the authors highlight the promise of further research.
December 2025 in “Frontiers in Nutrition” This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.
17 citations
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October 2015 in “Medicine and Pharmacy Reports” This article reviews current research on animal models for hair regrowth treatments and reports no new findings; it highlights the need for studies comparing therapy efficiency and long-term safety.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
26 citations
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December 2020 in “Nature metabolism” Martin-Perez et al. show that rapamycin's beneficial effects in a mouse model of Leigh syndrome are linked to the downregulation of protein kinase C.
June 2026 in “Quality in Sport” This narrative review found that combined oral contraceptives remain the primary treatment for hirsutism and acne in women with PCOS, but highlighted the need for further research to refine therapeutic options given the variable efficacy and emerging treatments like GLP-1 receptor agonists.
3 citations
,
June 2020 in “Open access rheumatology” This case report reviews the management of Rowell syndrome in a patient initially diagnosed with Rhupus syndrome and highlights their development of erythema multiforme after certain medications.
4 citations
,
October 2025 in “Molecules” This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
November 2025 in “Iraqi Journal of Science” In this study conducted on Iraqi individuals with celiac disease not on a gluten-free diet, researchers observed elevated serum urea and creatinine levels, which may indicate an increased risk of renal dysfunction, alongside decreased magnesium, zinc, and vitamin C compared to healthy controls.
7 citations
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May 2007 in “PubMed” This study found that women with androgenetic alopecia were more insulin resistant than healthy controls, suggesting the use of beta cell function and insulin sensitivity indices to measure insulin resistance in this population.
June 2004 in “Journal of Investigative Dermatology” Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
7 citations
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April 2013 in “Clinical and Experimental Dermatology” This study found that tianeptine may suppress the transition to catagen, promoting hair growth in a stress-induced alopecia areata mouse model.
66 citations
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July 2007 in “Journal of Molecular Medicine” This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.
April 2023 in “Journal of Cutaneous and Aesthetic Surgery” This review proposes a combination treatment scheme with a rotational approach for managing androgenetic alopecia, drawing on evidence for effectiveness, long-term use convenience, and patient acceptance, but presents no new clinical results.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.