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This study suggests that the paradoxical effects of androgens on hair growth are due to differential gene expression in hair follicles, possibly established during embryogenesis.

This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.

The abstract reports that non-cultured cellular grafting has become a prevalent and cost-effective method for treating stable vitiligo, with safety and effectiveness confirmed by two decades of studies. It critiques strict legislative oversight, suggesting it might unnecessarily increase costs and limit patient access.

In this study, activation of c-MycER in adult mouse epidermis rapidly induced proliferation and disrupted keratinocyte differentiation, causing changes similar to precancerous lesions, which regressed once c-MycER was deactivated.

This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

This study reports that Lef1 plays a crucial role in promoting bulge stem cell differentiation towards hair fate by activating β-catenin and downstream signaling pathways during hair follicle development.

This study found that C. obtusa oils promoted hair growth in shaved mice and increased the expression of a hair growth regulator, VEGF, in a cell line.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This study found that disrupting Smad4 signaling in young mice led to overactivation of follicle stem cells, causing hyperplasia and depletion of the stem cell niche.

This study found that melatonin significantly improved metabolic and reproductive parameters in PCOS-induced rats, with effects similar to metformin.

This study found that reduced expression of CD200R1 on monocyte-derived macrophages in rheumatoid arthritis patients was significantly associated with higher disease severity and an imbalance in Th17/Treg cells.

This study found that the Pseudomonas sp. T5-6-I strain significantly increased selenium accumulation and root hair density in Brassica oleracea, highlighting its potential for phytoremediation and biofortification.

This study found that women with polycystic ovary syndrome have elevated cardiovascular risk markers, with levels being higher in obese participants compared to non-obese participants.

This study found that deletion of c-Jun and JunB in mouse bulge hair follicle stem cells was sufficient to trigger psoriasis-like skin disease through thymic stromal lymphopoietin signaling.

This study found that alopecia areata patients had increased insulin resistance compared to controls, suggesting a potential link between inflammation, stress axis activation, and insulin resistance in this population.

The authors concluded that increased expression of the HSD11B1 gene in adipose tissue correlates with obesity markers and predicts insulin resistance, but this association is independent of polycystic ovary syndrome when adiposity is controlled for.

This study found that co-applying Curcuma aeruginosa extract or essential oil with minoxidil significantly increased minoxidil's skin penetration in an ex vivo setting, suggesting an improved topical treatment strategy for androgenic alopecia with greater efficacy and the potential for lower minoxidil doses.

This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.

This study found that Twist1 and Tcf4 synergistically regulate the hair follicle induction ability of dermal papilla cells by forming a complex with β-catenin, enhancing their biological properties.

In this study, certain genetic variations in the ESR1 and ESR2 genes were strongly associated with polycystic ovary syndrome and related metabolic issues in Tunisian women.

This study found that human C-tactile afferents respond to hair deflection, suggesting a functionally relevant anatomical relationship to hair follicles similar to that observed in mice.

This study found that engineered skin substitutes made with skin-derived precursors and epidermal stem cells can regenerate hair follicles after grafting into nude mice.

This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.

This study suggests that Lindera strychnifolia root extract may help restore a healthy microbial balance on the scalp in men with androgenetic alopecia after 83 days of treatment.

LIPH mutations cause woolly hair in some Chinese people.

This study found that human dermal stem/progenitor cells demonstrated greater proliferation and differentiation potential than hair follicle dermal papilla cells, which showed increased expression of hair regeneration markers.

This study found that CRP levels were elevated in alopecia areata patients, with an inverse linear association between serum vitamin D and CRP levels specifically noted in ophiasis AA.

This animal study found that finasteride, a 5-alpha reductase type 2 inhibitor, decreased dihydrotestosterone levels and c-Fos protein activation in the rat brain, but these effects may diminish after discontinuing the drug.

This review highlights that bacteriophage therapy shows promise for acne treatment by specifically targeting Cutibacterium acnes, but larger clinical trials and improved regulatory frameworks are needed for further development.

This study suggests that proteins CHI3L1 and CXCL5, secreted by recovery-state dermal papilla cells, may promote hair growth by stimulating the proliferation of outer root sheath cells.