![Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds](/images/research/6712367a-949f-47c7-a756-2bfe6316fc69/small/15331.jpg)
6 citations,
August 2004 in “Journal of Chemical Information and Computer Sciences” The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.
5 citations,
July 2018 in “Pediatrics” A 3-year-old girl developed scurvy symptoms that improved with vitamin C but relapsed when supplementation stopped.
4 citations,
November 2021 in “Journal of Clinical Medicine” Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
4 citations,
January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
2 citations,
July 2019 in “PLOS ONE” Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.
1 citations,
March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
1 citations,
April 2020 in “Clinical, Cosmetic and Investigational Dermatology” Acyclovir cream may slow down hair growth, suggesting it could be a new treatment for excessive hairiness.
1 citations,
January 2020 in “Journal of Crohn's and colitis” Many people with inflammatory bowel disease have a vitamin C deficiency, which can lead to scurvy symptoms.
Avicennia marina extract may help treat hair loss naturally.
August 2024 in “Skin Research and Technology” Omega-6 and LDL cholesterol increase the risk of hair loss.
Higher bad cholesterol levels are linked to more severe female pattern hair loss.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Madam C.J. Walker became the first self-made female millionaire in the USA by creating a successful hair care product for Black women.
May 2022 in “CMAJ. Canadian Medical Association journal” Rosella C. believes an earlier diagnosis of Cushing disease could have prevented severe symptoms.
June 2021 in “International journal of cosmetics and dermatology” Vitamin C and E may help with certain skin and hair conditions, but more research is needed to confirm their effectiveness.
June 2019 in “Kufa journal for veterinary medical sciences” Vitamin C deficiency causes severe skin problems in newborn dairy calves.
April 2018 in “Journal of Investigative Dermatology” Older mice healed wounds better but lost more weight and might have weaker immune systems afterward.
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
Patients with lichen planus should be tested for hepatitis C.
January 2011 in “Annals of dermatology/Annals of Dermatology” A woman's psoriasis improved after hepatitis C treatment with interferon, despite interferon's risk of worsening skin conditions.
November 2001 in “Hair transplant forum international” The document's conclusion cannot be provided because the document is not readable.
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
467 citations,
May 1999 in “Molecular Cell” The study explored the effects of activating the protooncogene c-Myc in the skin of transgenic mice, revealing that c-Myc activation led to rapid proliferation and disrupted differentiation of keratinocytes, resulting in conditions resembling precancerous lesions such as hyperplastic actinic keratosis. These changes were accompanied by angiogenesis and were reversible upon deactivation of c-Myc. Despite the potential for c-Myc to induce apoptosis, survival signals in the skin suppressed this effect, allowing for the development of benign, hyperproliferative lesions without progressing to malignancy. The study highlighted the role of c-Myc in skin homeostasis and its implications in skin carcinogenesis, suggesting that additional mutations would be necessary for malignant transformation.
60 citations,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
45 citations,
September 2001 in “Journal of Investigative Dermatology” Cyclosporin A promotes hair cell growth and affects protein kinase C levels.
41 citations,
August 2007 in “European Journal of Gastroenterology & Hepatology” A woman's total hair loss from hepatitis C treatment grew back after stopping the medication.
28 citations,
August 2014 in “Journal of Assisted Reproduction and Genetics” The VEGF +405G allele may increase the risk of PCOS in South Indian women.
26 citations,
May 2007 in “Differentiation” Foxn1 helps skin cells mature by controlling a specific protein's activity.
24 citations,
February 2015 in “Experimental Cell Research” NFIC helps human dental stem cells grow and become tooth-like cells.