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In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.

This study reported that paracrine factors, such as IGF-I and SCF, were reduced in balding hair follicles compared to non-balding ones, while inhibitory factors like TGFß-1 were increased, providing insights into the androgen action in hair follicles.

This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.

This study suggests that hairlessness in nude mice may be due to insufficient expression of phospholipase C-δ1, a molecule essential for normal hair development downstream of the Foxn1 gene.

In this review, researchers explored the roles of vitamins A, B3, C, D, and E in skin immunity, highlighting their potential as therapeutics for skin diseases due to their antioxidant, anti-inflammatory, and antimicrobial properties.

This study found that cortisol increases mac25/IGFBP-rP1 expression in osteoblast-enriched cells from fetal rat calvariae, indicating transcriptional regulation which may influence IGF and insulin effects in bone.

This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.

This study found that melatonin-loaded vitamin C-based nanovesicles improved hair thickness, density, and reduced hair loss in patients with androgenic alopecia more effectively than melatonin solution.

This study reported that while lichen planus was not significantly linked to hepatitis C virus infection, pruritus, dry skin, and hair loss were more common in HCV patients post-interferon treatment.

This article reviews the molecular interactions involved in hair follicle cycling and highlights the role of dermal papilla cells, but it presents no new research findings.

In this study, procyanidin B-2 and C-1 were found to promote hair growth by selectively inhibiting protein kinase C, supporting their potential use for hair-growing activity.

This article reviews the association between hepatitis C virus and systemic disorders like mixed cryoglobulinemia, highlighting potential autoimmune side effects from interferon-a2b treatments, and reports no new clinical results.

This study suggests that glycoproteins tenascin-C and tenascin-W may influence the migration and proliferation of CD34-positive stem cells in mouse whisker follicles.

This study found that NFI-C plays a crucial role in the transition from the telogen to anagen phase of the hair follicle cycle, affecting hair growth initiation in mice.

This study found that cucurbitacin I from bitter melon most effectively inhibited the growth of lung cancer cells and promoted hair cell growth in cell cultures.

This study found that Rumex japonicus extract may help reduce symptoms of atopic dermatitis by inhibiting inflammatory responses in both cell cultures and a mouse model.

This study found that the methanolic heartwood extract of Avicennia marina significantly inhibits 5α-reductase type 1, reducing 5α-DHT production by 52% in a cell-based assay with human hair dermal papilla cells.

This paper describes a case of epidermolysis bullosa simplex with muscular dystrophy associated with a novel PLEC mutation and diffuse alopecia, highlighting a potential genetic link that remains uncertain.

In this study, topical Emu oil delayed burn wound healing but increased hair follicle activity and collagen synthesis in Balb/c mice.

This study hypothesizes that a mummified 19th Century girl in San Francisco died of severe undernourishment potentially due to a bacterial-borne disease, highlighting historical health challenges mitigated by modern sanitation and medicine.

This case report observed that pulmonary arterial hypertension in a man with severe vitamin C deficiency resolved after vitamin C supplementation, suggesting a potential role of vitamin C in managing this condition.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.

In this study, micronutrient intake was associated with androgen levels in women with PCOS, with the association more pronounced in NA PCOS compared to HA PCOS groups.

This study found that anthralin and sodium dodecyl sulfate accelerated hair growth in mice, potentially involving different skin protein kinase C isoform responses.

In this study, overexpression of secretory phospholipase A2 Group-IIA in transgenic mice led to depletion of hair follicle stem cells and increased differentiation, linked to changes in histone modifications.

Silymarin improves hair follicle health better than vitamin C by boosting cell growth and reducing oxidative stress.

This case report detailed alopecia universalis developing shortly after hepatitis C treatment with peg-interferon, ribavirin, and telaprevir, suggesting potential immune-related links between interferon treatment and alopecia areata.

This study found that the Plcd3(mNab) mutation in mice worsens the alopecia caused by Plcd1 loss, suggesting synergistic effects between Plcd1 and Plcd3 on hair follicle health.