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This study found that transient activation of c-Myc in transgenic mice stimulates keratinocyte proliferation and sebocyte differentiation, affecting normal epidermal and hair follicle development.

This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.

This study found that 2-methoxyestradiol induces apoptosis in human prostate cancer cells by activating p53 through a pathway dependent on p38/JNK-mediated NFkappaB/AP-1 activation, with JNK-dependent Bcl-2 phosphorylation also playing a critical role.

This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.

In this study, a novel mutation in the glucocorticoid receptor gene was identified in a young woman, impairing glucocorticoid signaling and leading to generalized glucocorticoid resistance.

This study demonstrates that c-MYC overexpression in sebaceous glands affects differentiation via a regulatory axis involving the androgen receptor and p53, influencing carcinoma formation outcomes.

This study found that the co-ablation of C/EBPalpha and C/EBPbeta in adult mouse skin disrupted sebocyte differentiation and epidermal homeostasis, highlighting their critical roles in these processes.

This study suggests that Myc superfamily transcription factors may have distinct roles in different epithelial compartments of the human hair follicle, possibly influencing cell fate in the putative stem cell compartment.

In this study, trichoscopy highlights that hair diameter variability, vellus hairs, and the peripilar sign are key indicators for diagnosing androgenetic alopecia.

In this study, stress experienced by transmen during early stages of gender transition was associated with reduced nocturnal blood pressure decline and increased C-reactive protein levels.

This study found that in androgenetic alopecia, reduced stem cell factor production by dermal papilla cells may lead to decreased pigmentation in hair follicles.

This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.

This study found that c-Jun is essential for vitamin D receptor expression, and the vitamin D receptor inhibits c-Jun-dependent cell death through non-classical mechanisms independent of vitamin D3.

This study found that expression of certain mutant keratin genes in mice led to severe alopecia, suggesting a similar mechanism could cause hair loss in humans.

In this study, knockout of B-raf and C-raf genes in mice showed they are not needed for early melanocyte development, but are crucial for maintaining melanocyte stem cells, as evidenced by hair graying due to stem cell depletion.

This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.

This study found that C-reactive protein may enhance monocyte adhesion to endothelial cells through NOX-mediated oxidative stress, suggesting a potential mechanism for atherogenesis.

In this study, hs-CRP levels were not significantly associated with PCOS among Indian adolescent women, but showed a positive correlation with body mass index.

This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.

The study found that finasteride increased endoplasmic reticulum stress and reduced fertility in rats, effects that were alleviated by the administration of DA-9401.

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

This study found that recombinant IFN α-2b injections in patients with acute post-transfusion hepatitis C can suppress viral RNA and lead to normalization of serum ALT, though long-term prevention of chronicity remains unclear.

This study found that maternal iron-restricted diets increased alopecia incidence in IL-10-deficient mouse pups with mast cells, implicating mast cells as potential effectors in this process.

This study found that progesterone derivatives with chlorine or bromine substituents were effective in inhibiting 5α-reductase activity in human prostate and exhibited antiandrogenic effects in hamster flank organs.

This study observed that some patients with homozygous c.736T>A mutation in LIPH may have mild hypotrichosis with long hairs in adulthood.

This study suggests that the C-terminal of AHF is crucial for its binding to keratin bundles and modulating the keratin meshwork in hair follicles.

This study found that asynchronous differentiation in human anagen hair follicles involves specific localization of c-Myc and interrelated genes Max and Bin1 along the inner root sheath.

This study found that GPC1 is a crucial regulator of angiogenesis in human dermal microvascular endothelial cells, indicating its potential as a target for treating alopecia.

This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.

This study found that human C-tactile afferents respond to hair deflection, suggesting a functionally relevant anatomical relationship to hair follicles similar to that observed in mice.