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In this study, researchers found that simple hair clipping in mice induced dynamic plasticity and axogenesis in skin sensory axons, linked to follicular activation and HGF signaling.

This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.

This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.

This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.

HDAC1 is crucial for skin development and preventing tumors.

This study reports the successful generation of inducible pluripotent stem cells from mesenchymal stem cells derived from human hair follicles, marking a novel method of reprogramming these cells.

This study found that thalidomide increased peripheral lymphocyte counts and reduced inflammation in lupus erythematosus patients, but was associated with polyneuropathy, suggesting careful use in refractory cases.

This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.

This review highlights recent findings on the importance of signalling pathways in sebaceous gland morphogenesis and differentiation, but reports no new clinical results.

Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.

This study reports that Lef1 plays a crucial role in promoting bulge stem cell differentiation towards hair fate by activating β-catenin and downstream signaling pathways during hair follicle development.

This study found that patients with alopecia areata had significantly lower T cell numbers and reduced lymphocyte responses compared to healthy controls, correlated with hair loss severity and presence of antithyroid antibodies.

In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.

This review discusses genetic and epigenetic mechanisms that may contribute to aging and presents models suggesting that chromosomal changes could play a key role in the aging process; it reports no new experimental findings.

This study found that C. obtusa oils promoted hair growth in shaved mice and increased the expression of a hair growth regulator, VEGF, in a cell line.

The researchers found that plant extracts from Papaver rhoeas L., Clitoria ternatea L., and Carthamus tinctorius L. are effective natural cosmetic dyes, offering intense and stable colors without cytotoxicity.

This study found that Florida manatees have unique types of specialized nerve endings in their vibrissae, which assist in their sensory and manipulative functions in aquatic environments.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This study found that disrupting Smad4 signaling in young mice led to overactivation of follicle stem cells, causing hyperplasia and depletion of the stem cell niche.

This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.

In this study, hair samples from breast cancer patients showed increased β-sheet structures and lipid content, with spectral markers successfully identifying cancer in a blind test but also producing false positives.

This study found that melatonin significantly improved metabolic and reproductive parameters in PCOS-induced rats, with effects similar to metformin.

This study suggests that different melanocyte subpopulations in hair follicles have varying patterns of apoptosis and survival during the catagen phase, which may inform models for modulating melanocyte behavior in vivo.

This study found that transfollicular delivery using surfactant-based nanoparticles significantly enhanced antigen stability and immune response compared to other delivery methods, especially when combined with an adjuvant.

This study reported that tryptanthrin, a compound found in indigo naturalis, effectively suppresses non-melanoma skin cancer in mice by reducing inflammation, inhibiting cell proliferation, and blocking specific signaling pathways associated with tumor growth.

This study reported that thymol-loaded nanoparticles showed promise as an antibiotic-free treatment for acne by effectively targeting the infection without disrupting healthy skin microbiota.

This study observed that VEGF165 increases proliferation and migration but alters adhesion properties of cultured human hair follicle cells, indicating a potential role for VEGF/VEGFR-2 in hair follicle regulation beyond angiogenesis.

This study found that EGFR and MEK inhibitors may induce acneiform skin toxicities by interacting with the skin bacterium Cutibacterium acnes to increase IL-36γ and IL-8 production in keratinocytes.

This review discusses the relationship between polycystic ovary syndrome and inflammation, highlighting various inflammatory markers, but reports no new clinical results.