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The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.

This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.

This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.

This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.

This article describes adult female acne as a complex condition affected by genetic, hormonal, and environmental factors, with hormonal therapies highlighted as particularly valuable for treatment.

In this study, researchers found that an antibacterial toner can penetrate keratin and sebum plugs and exhibits bactericidal effects against Cutibacterium acnes, as evidenced by a decrease in viable cell counts within artificial plugs inoculated with the bacteria.

This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.

This study found that EGFR and MEK inhibitors may induce acneiform skin toxicities by interacting with the skin bacterium Cutibacterium acnes to increase IL-36γ and IL-8 production in keratinocytes.

This review discusses the multifactorial pathogenesis of acne and current treatment strategies including the use of isotretinoin and spironolactone, but reports no new clinical results.

This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.

This study suggests that Lindera strychnifolia root extract may help restore a healthy microbial balance on the scalp in men with androgenetic alopecia after 83 days of treatment.

In this study, researchers found that specific treatment parameters disrupted follicles and sebaceous glands, damaging the bacteria Cutibacterium acnes and promoting follicular remodeling, which may improve both inflammatory and noninflammatory acne lesions.

In this study, researchers observed significant differences in microbial composition between UV-induced fluorescent and non-fluorescent scalp areas in patients with androgenetic alopecia, noting a higher abundance of Cutibacterium in the fluorescent regions.

This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.

This study reported that thymol-loaded nanoparticles showed promise as an antibiotic-free treatment for acne by effectively targeting the infection without disrupting healthy skin microbiota.

This review highlights that bacteriophage therapy shows promise for acne treatment by specifically targeting Cutibacterium acnes, but larger clinical trials and improved regulatory frameworks are needed for further development.

This study found that in individuals with alopecia, scalp microbial diversity decreased while Cutibacterium acnes abundance increased, and that treating Cutibacterium acnes-infected mice with Lactobacillus plantarum L30 improved hair follicle health and hair growth, suggesting a potential new treatment pathway for alopecia.

Staphylococcus epidermidis affects hair growth and metabolism, suggesting it could help manage hair growth issues.

This study evaluated a novel hand-held low-level light therapy device for treating mild-to-moderate acne, finding it significantly reduced inflammatory lesions and moderate acne severity without severe adverse reactions, while also reducing Cutibacterium acnes viability in vitro.

This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.

Vitamin C-based nanovesicles effectively treat acne.

In this study, researchers found that Dlx3 plays a crucial role in regulating chromatin accessibility and gene transcription during keratinocyte differentiation in the epidermis, highlighting its potential impact on epidermal barrier formation and differentiation.

This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.

The researchers reported that using GoodRx.com enables patients to find the most affordable options for purchasing finasteride, a medication often not covered for androgenic alopecia, by comparing prices at local and mail order pharmacies in Washington, D.C.

The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.

This study found that the plant Clausena anisata exhibited promising antimicrobial, antioxidant, and anti-inflammatory activities against acne-causing bacteria and inflammation, suggesting its potential as a candidate for further anti-acne treatment research.

In this case study, scurvy was diagnosed in a middle-aged man on hemodialysis with food insecurity and undetectable vitamin C levels, highlighting the diverse risk factors and persistent challenges in managing vitamin C deficiency among patients with complex medical and social issues.

This study elucidates a mechanism for acne-like skin toxicity caused by EGFR/MEK inhibitors, involving an interaction with skin bacteria to trigger inflammation, which supports existing antibiotic treatment practices.

This study found that in Vdr-knockout mice, hair follicles fail to complete the catagen stage, leading to persistent epithelial strands and subsequent hair loss.

This study examines how skin microbiota and the gut-skin axis affect acne development, aiming to reveal mechanisms that could inform future treatment strategies for acne and other inflammatory skin conditions.