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Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

This study developed and validated an HPLC method for detecting a novel 5α-reductase inhibitor in human plasma, supporting its pharmacokinetic evaluation at low doses.

This study describes a validated UPLC-MS/MS method for quantifying finasteride in human plasma, demonstrating higher specificity, improved resolution, increased sensitivity, and faster analysis times compared to conventional HPLC-MS/MS methods.

This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.

This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.

This study reported that a novel bilayer wound dressing made from PLCL nanofibers and keratin hydrogel, loaded with FGF-2, promoted skin healing and showed potential for use in skin tissue engineering.

This study found that oral administration of naturally safe active polypeptides from marine shellfish promoted scarless dermal wound healing in mice, potentially via effects on inflammation, fibroblast activity, and the "skin-gut" axis.

The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.

In this study, a novel nanocomposite hydrogel was developed for diabetic wound care, demonstrating superior tissue adhesion, antibacterial properties, and healing capabilities in vivo and in vitro, while also allowing real-time pH monitoring to aid clinical management.

This study examined the microscopic characteristics of hair or feather in five animal drug components of the Shenrongbian pill, identifying distinctive medulla cell shapes and hair cuticle patterns for each component.

This study developed methods for detecting carboxy-finasteride in urine for doping control, demonstrating detection up to 49 hours post-administration with high precision and accuracy.

This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.

The composite dressing improved wound healing and hair growth in mice.

This study found that treating damaged hair with maleic-modified amino silicone oil created a highly hydrophobic surface, reducing water content and improving hair's mechanical properties and thermal stability.

This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.

This study found that cedrol nanoemulsions significantly promote hair follicle regeneration and reduce DHT levels in an androgenic alopecia mouse model, suggesting potential efficacy in AGA treatment.

This study observed that mercury-lamp irradiation may cause cleavage of disulfide bonds in keratins of white hair, leading to the formation of thiols in laboratory settings.

This study suggests that pulsed wave photobiomodulation could be a promising treatment for androgenetic alopecia by enhancing dermal papilla cell function through specific light parameters, particularly frequency.

Photobiomodulation helps protect hair follicle cells from damage caused by DHT.

UVA exposure worsens hair loss by activating a specific cell pathway.

In this study, researchers observed that blue LED irradiation enhanced cosmetic permeation, increased diameter, and improved resistance of hair fiber in Caucasian and Asian ethnic groups, whereas African hair showed less change.

In this study, the combination of low level light therapy with arginine, arterial extract, or biotin tripeptide-1 was associated with improvements in hair density and follicle structure in androgenic alopecia.

In this study, researchers found that chitosan-coated PLGA nanoparticles improved the iontophoretic transdermal delivery of the positively charged hydrophilic drug donepezil hydrochloride in an ex vivo rat skin model, achieving 2.2 times higher skin accumulation compared to non-coated nanoparticles.

In this study, lecithin/n-propanol/isopropyl myristate/water/tetracaine hydrochloride microemulsion was found to be a safe carrier for transdermal drug delivery in animal models, with analgesic effects on Wistar rats.

This study found that melanin granules in black human hair are key dyeing regions for oxidative hair coloring, as confirmed by nanoscale mass spectrometry analysis detecting deuterium ions.

This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.

In this study using a porcine skin model, the researchers reported that smaller curcumin nanocrystals in xanthan gum gel showed higher passive skin penetration, while larger particles achieved deeper follicular accumulation.

This study describes the presence of holes in hair fibers, absent in hair follicles, likely forming from daily care actions and removal of extractable substances.

This study suggests that extracting hair proteins at relatively high temperatures may enhance their hemostatic properties by altering their secondary structure and increasing the precipitation of soluble fibrinogen.

This study explores novel alopecia treatments targeting lactate dehydrogenase pathways and improving drug delivery through technologies like phototherapy and soluble microneedles, though practical application challenges remain, necessitating further research for clinical use.