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Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.

Patients with rapidly progressive alopecia areata often have a better outlook and shorter disease duration, with regrown fine hairs and no past alopecia being positive signs.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Combination therapy with steroids and pimecrolimus improved or stabilized hair loss in most patients with Frontal Fibrosing Alopecia, who also had a high rate of hypothyroidism.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Putting ketoconazole on the skin can help mice grow hair.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.