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This review of stem cell-based tissue engineering treatments in preclinical burn wound models reports promising improvements in skin repair, suggesting potential as an enhanced therapy for burn wounds.

In this study, topical Emu oil delayed burn wound healing but increased hair follicle activity and collagen synthesis in Balb/c mice.

This study reported that adipose-derived stem cells may promote burn wound healing and skin appendage regeneration in a rat model, suggesting a potential approach for improving burn treatments.

In this study, poly (ɛ-caprolactone)–chitosan–poly (vinyl alcohol) nanofibrous scaffolds used on canine skin wound models were found to significantly accelerate healing rates of excision and burn wounds, without inducing immunogenic reactions.

This study found that Cur-Fe-mesoporous silica nanoparticles synergistically inhibited scar formation and promoted hair follicle regeneration in skin burn wound healing by releasing bioactive components like SiO32−, Fe3+, and Fe-Cur chelates.

This study reported that a self-pumping organohydrogel dressing equipped with hydrophilic fractal microchannels significantly increased exudate drainage efficiency and enhanced burn wound healing in mice, reducing dermal cavity size and accelerating blood vessel and hair follicle regeneration compared to commercial dressings.

In this study, researchers developed a composite electrospun wound dressing containing strontium zinc silicon bioceramics, which significantly activated hair follicle stem cells and promoted hair follicle and capillary regeneration in deep burn wounds, suggesting a promising approach for burn wound healing.

In this study, researchers found that Wnt4 overexpression increased the thickness of burn wounds by promoting epidermal cell migration and activating the canonical Wnt signaling pathway.

This study found that using RADA16-I dressing led to more vigorous hair growth on deep burn wounds compared to other biological materials.

In this study, neonatal mouse mesenchymal cells showed hair-inducing capabilities, which were lost during in vitro propagation but could be partially restored through specific high-density culture methods.

This study found that a mixture of Lawsonia inermis L. powder and honey could significantly speed up burn wound healing and promote hair growth in rabbits compared to control and honey-alone treatments.

This review explores the molecular mechanisms through which NGF may enhance burn wound healing by reducing healing time and improving scar quality, but it presents no new clinical results.

In this rat study, Coriaria sinica Maxim extract significantly improved burn wound healing by enhancing epithelial growth and promoting hair regrowth, possibly through early-stage protein and mRNA expression changes.

This study found that hair follicle stem cells could enhance burn wound healing and improve tissue tensile strength in rats.

Platelet-rich fibrin speeds up burn wound healing in rabbits.

This study suggests that a sandwich-structured wound dressing with bioceramic and polylactic acid layers may improve burn wound healing by absorbing exudates and promoting hair follicle regeneration.

In this study, autologous platelet-rich plasma was associated with improved burn wound healing in a 45-year-old male, showing potential as an adjunctive therapy, but broader trials are needed to confirm its effectiveness.

This study suggests that tailoring burn wound treatment to the timing of prevalent cell death types could improve therapy outcomes, as autophagy and apoptosis show distinct temporal patterns post-burn in a rat model.

In a murine burn wound model, this study found that an enhanced fractal self-pumping dressing significantly reduced wound area and tissue edema by efficiently draining excess exudates.

This study reports that Cur@CMCTS-Tk hydrogel effectively accelerated wound healing and tissue regeneration in rats by scavenging excess reactive oxygen species and protecting human fibroblasts from oxidative damage.

New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.

This study found that a sericin-based hydrogel containing Psidium guajava L. extract significantly improved healing of full-thickness burn wounds in mice, with 89.66% wound closure by day 15 compared to 37.16% in controls, and exhibited beneficial effects on inflammation and oxidative stress markers.

This study reviews emerging techniques in acute burn wound therapy, noting innovations such as advanced imaging for better wound assessment and new closure strategies aimed at improving healing, graft survival, and scarring outcomes, while emphasizing the need for further research to validate these methods.

This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.

In this mouse study, researchers reported that a 3D bioprinted hydrogel scaffold containing adipose-derived mesenchymal stem cells and nitric oxide enhanced burn wound healing by promoting neovascularization through the VEGF signaling pathway.

This study found that a new topical nitric oxide gel significantly accelerated burn wound healing in mice by enhancing re-epithelialization, hair follicle regeneration, collagen deposition, and angiogenesis compared to controls.

Moist Exposed Burn Ointment speeds up healing of diabetic wounds.

This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.

This study found that stem cell therapy significantly improved burn healing rates in animal models, with hair follicle stem cells showing particularly strong effects.

In a mouse model of infected burns, this study found that treatment with recombinant fusion peptide EK significantly decreased Pseudomonas aeruginosa colony count and improved wound healing rates compared to controls.