17 citations
,
January 2016 in “Dermatology research and practice” In this study, topical Emu oil delayed burn wound healing but increased hair follicle activity and collagen synthesis in Balb/c mice.
2 citations
,
January 2017 in “Recent clinical techniques, results, and research in wounds” This study found that adding galeotomies to subgaleal tissue expander placement for post-burn alopecia resulted in faster scalp expansion and reduced complications of expander extrusion.
9 citations
,
February 2013 in “Plastic and Reconstructive Surgery” This article reviews options and principles for reconstructing defects of the scalp, skull, orbit, and maxilla, but reports no new clinical results.
30 citations
,
February 2022 in “Stem Cell Reviews and Reports” This review of stem cell-based tissue engineering treatments in preclinical burn wound models reports promising improvements in skin repair, suggesting potential as an enhanced therapy for burn wounds.
18 citations
,
March 2018 in “Archives of Plastic Surgery” This article reviews the use of superficial temporal artery island flaps for facial reconstruction and provides a systematic approach for managing composite facial defects, reporting no major complications in 72 patients.
13 citations
,
November 2024 in “Frontiers in Microbiology” This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.
10 citations
,
January 2018 in “Organogenesis” This study found that epidermal stem cell-specific Jag1 expression levels are crucial for effective wound healing and scar reduction, and porcine acellular dermal matrix treatment enhances this process in mice by boosting Notch/Jagged1 signaling.
5 citations
,
May 2005 in “Seminars in Plastic Surgery” This article reviews the use of micrografts and minigrafts for facial and scalp hair reconstruction, noting it is safe, predictable, and achieves high patient satisfaction, but it presents no new clinical data.
4 citations
,
January 2008 in “Facial Plastic Surgery” This article reviews postoperative strategies to improve aesthetic outcomes of skin paddles used in microvascular free tissue transfer for head and neck reconstruction but offers no new clinical results.
1 citations
,
February 2020 in “International Surgery Journal” This study found that medical students have limited awareness and understanding of plastic surgery beyond cosmetic procedures, prompting the development of new educational modules to enhance their knowledge.
August 2024 in “Anatomía Digital” This study reviewed literature on reconstructive surgery, highlighting its role in restoring form and function after significant damage, and discussed common techniques, technological advancements like 3D printing, and challenges, including ethical and psychological considerations, emphasizing the importance of comprehensive patient care and expectation management.
January 2025 in “Open Medicine” This study found that high-concentration cell-free adipose extract effectively reduced collagen deposition and blood vessel formation in a rabbit ear model, showing promise for preventing and treating hypertrophic scars.
2 citations
,
January 2020 This article reviews various techniques for treating scars on different body parts and recommends combining methods based on individual scar needs, but it reports no new clinical results.
9 citations
,
May 2012 in “Journal of Craniofacial Surgery” This study reports that reconstructing perioral soft tissue defects with submental tissue resulted in satisfactory aesthetic outcomes and minimal donor-site morbidity.
26 citations
,
July 2006 in “Current Opinion in Otolaryngology & Head and Neck Surgery” This review discusses advancements in techniques for scalp reconstruction, highlighting improved cosmetic outcomes and reduced morbidity, but reports no new clinical results.
8 citations
,
March 2009 in “Aesthetic Plastic Surgery” This study found that the "flying-wings" expanded scalp flap technique effectively restored hemiscalp defects in children following burns, achieving pleasing aesthetic results and proper hair growth direction with minimal complications.
4 citations
,
November 2015 in “Aesthetic Plastic Surgery” Using tissue expanders for scalp reconstruction in patients with extensive Aplasia Cutis Congenita is effective and has minimal complications.
9 citations
,
November 2018 in “Drug Discovery Today” This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.
35 citations
,
October 2017 in “Signal Transduction and Targeted Therapy” This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.
March 2026 in “Frontiers in Cell and Developmental Biology” This meta-analysis found that autologous cell-based therapies, especially stromal vascular fraction, significantly improved atrophic acne scars over control treatments, enhancing both clinical and patient-reported outcomes.
2 citations
,
August 2011 in “InTech eBooks” New methods for growing skin cells can improve skin grafts by building blood vessels within them.
January 2025 in “Scripta Medica” This review suggests that natural compounds, particularly hydrolates, may improve burn wound healing and counter antibiotic resistance through their anti-inflammatory, antioxidant, and antimicrobial properties, offering promising complementary interventions.
April 2026 in “Journal of Pharmaceutical Investigation” This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.
October 2025 in “Indian Journal of Plastic Surgery” This review reports significant advancements in plastic surgery using stem cell therapies for aesthetic and reconstructive applications, including grafting and wound healing, though it underscores the need for continued research to address regulatory, ethical, and standardization issues.
2 citations
,
September 2023 in “Scientific reports” This study reports that zinc oxide or silver nanoparticles capped with vitamin A or E, incorporated into wheat gluten films, showed significant potential in promoting burn wound healing in mice by facilitating wound contraction, re-epithelialization, and collagen deposition, while also exhibiting antioxidant and antibacterial properties.
11 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses the use of tissue expansion combined with older surgical techniques to repair large scalp defects and reports no new clinical results.
178 citations
,
August 2016 in “Advances in wound care” This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
7 citations
,
September 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” In this randomized controlled trial, occipital donor sites for split-thickness skin grafts showed superior re-epithelialization, reduced pain, fewer complications, and better cosmetic outcomes compared to femoral donor sites.
20 citations
,
December 2010 in “Burns” This study found that longitudinal partial follicular unit transplantation may be an effective method for regenerating hair follicles and achieving satisfactory cosmetic outcomes in patients with facial and scalp burns, while preserving the donor area.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.