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Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Zinc is effective for treating various skin conditions, including warts and acne.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Hair follicle regeneration needs special conditions and young cells.

Smart biomaterials that guide tissue repair are key for future medical treatments.

The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.