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This study found that applying BMP2 stimulated limited regeneration of the amputated P2 bone in mice, but only when applied during a specific "regeneration window" after injury.

This study found that in adult mouse skin, reduced levels of histone H3 K4/K9/K27me3 during hair follicle stem cell quiescence are linked to proper tissue homeostasis.

This study found that placental growth factor (PlGF) enhanced hair shaft elongation and accelerated hair follicle growth, suggesting its potential as a therapeutic target for alopecia.

This study found that the PI3K-Akt signaling pathway is essential for regenerating new hair follicles when epidermal stem cells and skin-derived precursors are combined, suggesting potential therapeutic applications for hair regeneration.

This study reports that using nanogel and layer-by-layer self-assembly to encapsulate single dermal papilla cells can form cell spheroids that regenerate hair follicles successfully in a hair follicle regeneration model.

This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

This study suggests that adipose-derived mesenchymal stem cells from diabetic mice can enhance wound healing by promoting fibroblast growth, migration, angiogenesis, and differentiation into fibroblasts and endothelial cells.

This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.

This review discusses the common dermatologic side effects of epidermal growth factor receptor inhibitors and provides practical guidance for recognizing and managing these effects; it reports no new clinical results.

This study found that in squamous cell carcinomas, the inhibition of the tumor-suppressor function of TAp73β by ΔNp63α occurs through promoter squelching, not direct protein interaction.

This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.

This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.

This study found that Wnt3a increased beta-catenin signaling and upregulated specific genes in cultured human dermal papilla cells, enhancing their response to PGE2 and potentially aiding hair growth.

This study reports the purification of a specific sulphotransferase from rat liver that catalyzes the sulphation of minoxidil, potentially implicating it in minoxidil's bioactivation.

This review discusses the potential of three-dimensional printed mesoporous scaffolds for drug delivery applications, particularly for bone cells and tissues, but reports no new clinical results.

This study found that ginsenoside Rb1 promoted the growth of mink hair follicles and dermal papilla cells, potentially through activating the PI3K/AKT/GSK-3β signaling pathway.

This study found that exercise decreases the expression of 5αR1, thereby enhancing the PI3K/AKT signaling pathway in PCOS rats.

This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.

Skin cells can help create early hair-like structures in lab cultures.

This study observed that selectively activating activin in the epidermis of mice enhanced reepithelialization during wound healing without altering the quality of the healed wound.

This study found that Sp6 overproduction in ameloblast-lineage cells increased cell proliferation and ameloblastin expression, suggesting that Sp6 promotes amelogenesis by inhibiting follistatin gene expression.

This case report describes a 27-year-old woman with lupus erythematosus whose biopsy findings indicated that lupus panniculitis can mimic alopecia areata, leading to temporary hair loss.

This study concluded that GLCAT14A-C genes are crucial for the function of glucuronic acid transfer to AGPs in Arabidopsis, affecting various growth and reproductive traits such as seed germination and root hair growth.

In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.

This review examined dermatologic symptoms associated with COVID-19 in 2,560 patients, with chilblains/pernio-like lesions being the most common, suggesting these symptoms may aid in early identification of cases.

This study found that ancient and modern Chinese goats share close genetic ties, originating from the Fertile Crescent, with genetic divergence influenced by China's climatic divisions.

In this study, iNKT10 cells were found to play a significant role in preventing and treating alopecia areata in a humanized mouse model, suggesting these cells could have potential in managing related autoimmune disorders.

This study found that in psoriasis patients, the K17 protein probably functions as an autoantigen, with the HLA-Cw*06:02 risk genotype strongly linked to the T cell response size.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.