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The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Dermatopathology has made significant progress but many skin diseases remain incurable, requiring ongoing research.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.

Innovative biomaterials show promise in healing chronic diabetic foot ulcers.

Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.

Preserving and accessing historical research is crucial for ongoing scientific progress.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

Polyglutamic acid is a valuable, sustainable ingredient for skincare and haircare products.