research Removing All Obstacles: A Critical Role for p53 in Promoting Tissue Renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
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research Tissue Regenerative Delays and Synthetic Lethality in Adult Mice After Combined Deletion of ATR and TRP53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin
Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
research Correction to: Toxicity of the Pharmaceuticals Finasteride and Melengestrol Acetate to Benthic Invertebrates
Finasteride and melengestrol acetate are toxic to benthic invertebrates.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research The Pediatrician and the Sexually Active Adolescent
Pediatricians should advise sexually active teens on safe sex and STD prevention, and discuss contraceptive options and their side effects.
research Development of a Complex Skin Organ in Human Induced Pluripotent Stem Cell-Derived Organoids
Scientists created skin-like structures from stem cells that include features like hair and sweat glands.
research The Color of Skin: White Diseases of the Skin, Nails, and Mucosa
The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.
research Reporting in Clinical Studies on Platelet-Rich Plasma Therapy Among All Medical Specialties: A Systematic Review of Level I and II Studies
The review concluded that reporting on PRP therapy is often incomplete, leading to uncertainty about its effectiveness.
research Dermatoscopy Case of the Month: Trichodysplasia Spinulosa
A man with a weakened immune system was diagnosed with a rare skin condition called trichodysplasia spinulosa using skin examination techniques.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Patient Satisfaction and Complications Following Laser Hair Removal in Ethnic Skin
Most patients with dark skin were satisfied with laser hair removal and had few complications.
research Cultured Human Skin Fibroblasts: A Model for the Study of Androgen Action
research Serum Testosterone Levels in Surgeons During Major Head and Neck Cancer Surgery: A Suppositional Study
Surgeons' testosterone levels significantly increase during major head and neck cancer surgeries.
research The Health-Promoting Properties of Seaweeds: Clinical Evidence Based on Wakame and Kombu
Wakame and kombu seaweeds offer various health benefits like antioxidant and anticancer effects.
research Protein Loss in Human Hair from Combination Straightening and Coloring Treatments
Straightening and coloring hair, especially with sodium hydroxide, greatly increases protein loss.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Skin Aging in Women: Pathophysiology and Treatment
The document concludes that skin aging in women can be caused by UV exposure and hormonal changes, and treatments like hormone replacement therapy and various skin therapies can help.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
research Sources of Variation in Hair Cortisol in Wild and Captive Non-Human Primates
Hair cortisol levels in primates are useful for stress assessment but vary by age, sex, species, and hair collection methods.
research Correction to: Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
research The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams
Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Quiescent Tissue Stem Cells Evade Immune Surveillance
Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
research Automated Assessment of Tumor Infiltrating Lymphocytes Informs Mortality in Thin Melanoma
An automated system can predict death risk in thin melanoma by analyzing immune cells.
research Wound Healing
Wound healing is complex and requires more research to enhance treatment methods.
research Circadian Clock-Mediated Control of Stem Cell Division and Differentiation: Beyond Night and Day
The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.