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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

Allopregnanolone changes gene expression in glioblastoma cells.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Y27632 increases cell growth through EGFR signaling, not ROCK1/2.

Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Injecting 2 ml of TEEV every 4 weeks is better because it has the same benefits but fewer side effects.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Using lasers and fat grafting before hair transplant improves hair growth on scarred skin.