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Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

3D bioprinting is useful for making tissues, testing drugs, and delivering drugs, but needs better materials, resolution, and scalability.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Facial proportion is important in hair restoration surgery.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The new SIS-PEG sponge is a promising material for skin regeneration and hair growth.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.

Fat cells are important for tissue repair and stem cell support in various body parts.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Scalp cooling devices need to be powerful enough to overcome heat loss and reach the right temperature to prevent hair loss from chemotherapy.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Septin4 helps kill colon cancer cells by working with the protein BAX.

Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

The case emphasizes the need for careful screening in children for insulin resistance and related conditions.

Understanding how fetal wounds heal could help improve healing in adults.

Insulin resistance may contribute to hair loss in people with androgenic alopecia.

An 86-year-old man with prostate cancer was diagnosed with a rare, low-grade breast cancer and underwent surgery but declined additional hormone therapy.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Using tissue expanders and hyaluronidase in scalp reduction surgery allows for more scalp removal and easier surgery.