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Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Higher early lead exposure is linked to delayed puberty in girls.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Finasteride may help some women with hair loss, but better options exist.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Cooler scalp temperatures during chemotherapy may prevent hair loss.

Preventive measures and effective management are crucial for reducing skin side effects in cancer treatment.

Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Babies who gain weight quickly, especially in the first 3 months, may start puberty earlier.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Women who had cancer treatment feel both positive and negative about their bodies.

Japanese infants fed hydrolysate formula may have low biotin levels.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Testosterone patches can modestly improve sexual function in postmenopausal women not on estrogen therapy.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.

A man with a rare adrenal cancer showed unusual symptoms and died four months after diagnosis.

Severe acne in a young girl may indicate underlying hormonal issues.

Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

Permanent hair loss from chemotherapy significantly impacts patients' mental health and social life, highlighting the need for better patient education and support.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.