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Radiotherapy can cause rare changes in hair color, which should be discussed with patients.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Polymeric nanoparticles show promise for treating skin diseases.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Vitamin D and its receptor may help prevent skin cancer.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Mutations in certain receptors can cause diseases and offer new treatment options.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Lower SMAD2/3 activation predicts more severe skin cancer.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Clinicians should understand tattoos to manage health issues, as tattoos can cause complications and affect medical assessments.

A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.

The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.