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SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

Fat cells are important for tissue repair and stem cell support in various body parts.

Regenerative medicine may help reduce radiotherapy side effects like skin cancer, fibrosis, pain, and hair loss.

WNT10B is linked to cancer development and affects survival and disease progression in various cancers.

Targeting colon cancer stem cells might lead to better treatment results.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Stem cells can help other stem cells by producing supportive factors.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.