September 2023 in “Fides et Ratio” The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
2295 citations,
August 2012 in “The international journal of transgenderism/International journal of transgenderism” The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.
855 citations,
June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
418 citations,
June 2003 in “Endocrine Reviews” While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.
251 citations,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
244 citations,
September 2008 in “Annual Review of Genomics and Human Genetics” The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.
86 citations,
May 2013 in “American journal of obstetrics and gynecology” Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.
53 citations,
October 2018 in “Aesthetic Surgery Journal” Google Trends data on facial cosmetic procedures matches actual surgery numbers, showing it can help plastic surgeons understand public interest.
44 citations,
January 2008 in “Fertility and Sterility” Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.
13 citations,
September 2019 in “Scientific Reports” High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
10 citations,
February 2016 in “The Journal for Nurse Practitioners” Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.
9 citations,
April 2019 in “Journal of structural biology” Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
6 citations,
May 2022 in “Research and reports in urology” Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
3 citations,
January 2007 in “Elsevier eBooks” The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
2 citations,
August 2016 in “Experimental Dermatology” Finasteride treats baldness but may cause lasting sexual side effects.
January 2024 in “Wiadomości Lekarskie” Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.
37 citations,
October 2015 in “PeerJ” Perming significantly changes hair's molecular structure, while shampoo and conditioner do not.
30 citations,
January 2023 in “EFSA journal” Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
11 citations,
January 2018 in “International Journal of Trichology” The true incidence of post-Finasteride syndrome is unclear, and more research is needed.
3 citations,
February 2005 in “Lung Cancer” The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
December 2024 in “IntechOpen eBooks” Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
28 citations,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
9 citations,
September 2014 in “Cancer Epidemiology, Biomarkers & Prevention” Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.
33 citations,
May 2015 in “JAMA Dermatology” Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.
2 citations,
November 2011 in “InTech eBooks” Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
July 2019 in “Mayo Clinic proceedings” The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.
September 2003 in “Journal of the Royal Society of Medicine” Understanding breast cancer requires considering both medical advancements and social influences.
15 citations,
March 2018 in “Cancer Medicine” Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.
May 2011 in “Expert Review of Endocrinology & Metabolism” Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.
168 citations,
December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.