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Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Higher doses of cranial irradiation are linked to permanent hair loss.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Having enough iron improves the effectiveness of a specific hair loss treatment in women.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.