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Active vitamin D3 might protect hair follicles from radiation damage.

Menopause affects hair and skin; more research needed for treatment.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Genital rejuvenation is becoming popular for improving genital appearance and function in both men and women.

A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Finasteride treats baldness but may cause lasting sexual side effects.

Severe acne in a young girl may indicate underlying hormonal issues.

Botulinum toxin is used for neck, shoulder, calf, and ankle slimming, and hair loss treatment, but can cause muscle weakness and atrophy with regular use.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

The study found unique skin changes in a rare type of alopecia linked to a skin condition called linear morphea.

Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.

Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.

Topical vitamin D3 does not prevent hair loss from chemotherapy.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.