26 citations,
December 2006 in “Endocrinology” A cream with a specific hormone blocker increases hair growth in mice.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
December 2020 in “한국인그리에학회지” Astringent persimmon fruit extract may help hair grow longer and cover more area without increasing the number of hair follicles.
December 2020 in “한국인그리에학회지” Astringent persimmon fruit extract may help increase hair length and coverage without increasing the number of hair follicles.
3 citations,
February 2014 in “Dong-ui saengni byeongni hakoeji” Microneedle roller therapy could help treat hair loss by promoting hair growth.
March 2019 in “The International Journal of Advanced Smart Convergence” Radish saponin extract may help grow hair in balding mice.
January 1992 in “Proceedings of the New Zealand Society of Animal Production” Ferret hair growth starts between 0 and 4 days after melatonin treatment, with cell growth peaking in the hair germ and declining as the hair matures.
829 citations,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
9 citations,
January 2006 in “Cutaneous and ocular toxicology” L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers created a 3D-printed skin model that grew human hair when grafted onto mice by improving blood supply to the grafts.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
271 citations,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
238 citations,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
137 citations,
October 2009 in “The American journal of pathology” Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
50 citations,
August 1999 in “Experimental dermatology” The control system for hair growth cycles is not well understood and needs more research.
37 citations,
September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
33 citations,
May 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
29 citations,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
28 citations,
March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
27 citations,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
23 citations,
May 1998 in “Journal of Dermatological Science” Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.
12 citations,
December 2009 in “Amino Acids” Putting α-methylspermidine on mouse skin can start hair growth.
9 citations,
December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
7 citations,
October 2018 in “BMC genomics” Key genes can rewire networks, changing skin appendage types.
3 citations,
March 2016 in “Journal of Cosmetic Dermatology” GPIGS peptide increases thick hair growth in balding Japanese men.
2 citations,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
2 citations,
May 2020 in “Journal of visualized experiments” Controlled light treatment in mouse skin speeds up healing and hair growth.