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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Apoptosis is essential for human skin development and forming a functional epidermis.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

New effective scar treatments are urgently needed due to the current options' limited success.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

CDP is crucial for lung and hair follicle cell development.

Latanoprost can make eyelashes longer, thicker, and darker.