research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function
The Hairless gene is crucial for healthy skin and hair growth.
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research Abstracts
Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Post-Finasteride Syndrome: When Will We Get the Courage to Fight the Dictating Pharma Industry Despite Awareness of Sexual, Neurological, and Metabolic Side Effects in Young Men for Over a Decade
Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
research Effect of Finasteride Treatment in Male Rat: Depressive-Like Behavior and Related Parameters
research Targeting Smoothened for Therapeutic Gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Twins With Psychiatric Features and a Nonsense HRAS Variant Affecting Transcript Processing
A new HRAS gene variant may cause a range of symptoms including intellectual disability and psychiatric issues.
research Endocrine Intervention for Transsexuals
Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
research Autotaxin-LPA Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism
Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
research Role of Allopregnanolone Biosynthesis in Acute Stress-Induced Anxiety-Like Behaviors in Mice
Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Subcellular Localization of the Five Members of the Human Steroid 5α-Reductase Family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research Roles of Steroid Receptors in the Lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Presence of Mast Cells and Mast Cell Degranulation in Scalp Biopsies of Telogen Effluvium
The study suggests that mast cells might be involved in the hair loss condition telogen effluvium and could be a target for treatment.
research Montagna Symposium 2016: The Skin, Our Sensory Organ for Itch, Pain, Touch, and Pleasure
The symposium highlighted the skin's role in sensing itch, pain, touch, and pleasure, and discussed new research and techniques for understanding and treating these sensations.
research Effect of Neurosteroids on Basal and Stress-Induced Oxytocin Secretion in Luteal-Phase and Pregnant Sheep
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
research Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line
PROTO1 and PROTO2 protect against hearing damage.
research Pre-Receptor Regulation of the Androgen Receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy
Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
research Extra-Intestinal Manifestation of Celiac Disease in Children
Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Neurosteroid-Sensitive δ-GABAA Receptors: A Role in Epileptogenesis?
Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
research Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition from Telogen to Anagen Phase
Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.
research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.