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Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.

Lespedeza cuneata extract may help treat enlarged prostate.

Certain Egyptian Sabal fruit extracts may help treat anti-androgenic diseases like benign prostatic hyperplasia.

Methylation in specific gene region causes finasteride resistance in some BPH patients.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Finasteride causes sperm production decrease in Mesocricetus auratus.

Androgen-modulating drugs do not significantly change the heat sensitivity of prostate cancer cells.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Stopping tamsulosin one month before cataract surgery reduces eye surgery complications in rats.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

KY19382 helps regrow hair and create new hair follicles.

DA-9401 helps protect rat testis from finasteride damage.

Certain drugs that block specific enzymes can help treat prostate diseases.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.