research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
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research Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research The Naked Truth: Sphynx and Devon Rex Cat Breed Mutations in KRT71
Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.
research Fever And Rash As Initial Signs Of Systemic Autoimmune Disease: Case Report
Fever and rash can be early signs of lupus.
research Hyperandrogenism and Menstrual Imbalance Are the Best Predictors of Metformin Response in PCOS Patients
High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
research The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia
A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Iron-Deficiency Anemia During Childhood
Children need early diagnosis and treatment for iron-deficiency anemia to prevent learning problems and promote health.
research Transcriptomic Analyses of Regenerating Adult Feathers in Chicken
Chicken feather growth involves specific genes and shares similarities with hair development.
research The Genetics of Autism and Steroid-Related Traits in Prenatal and Postnatal Life
Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.
research Application of Baricitinib in Dermatology
Baricitinib shows promise as a new treatment for certain skin conditions like alopecia areata.
research Dermoscopy of Hair and Scalp Disorders (Trichoscopy) in Skin of Color—A Systematic Review by the International Dermoscopy Society Imaging in Skin of Color Task Force
More research is needed to understand hair and scalp disorders in people with skin of color.
research Acne and Acneiform Eruptions
Early treatment of acne is crucial to prevent scarring and psychological effects.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research The First Visit: Consultation and Workup Before Sperm Banking
A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
research Hypothyroidism with Multiple Associations: Case Report
The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.
research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research The Pediatrician and the Sexually Active Adolescent
Pediatricians should advise sexually active teens on safe sex and STD prevention, and discuss contraceptive options and their side effects.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Pemphigus Foliaceus in 91 Dogs
Both treatments for pemphigus foliaceus in dogs are effective, but combination therapy has more side effects.
research A Prospective Observational Study of Polycystic Ovarian Syndrome Among Adolescent and Young Girls at Tertiary Care Hospital
The study found that 7.21% of young girls have polycystic ovarian syndrome, with symptoms like irregular periods, abnormal hair growth, and acne. Early diagnosis is important to prevent long-term complications.
research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant
Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Expression of Hypothalamic-Pituitary-Thyroid Axis Related Genes in Human Skin
Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
research Insulin Resistance and Elevated Androgen Levels: A Major Cause of Polycystic Ovary Syndrome
Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
research Reduced Cell Cohesiveness of Outgrowths from Eccrine Sweat Glands Delays Wound Closure in Elderly Skin
Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.
research Oil Body Bound Oleosin-rhFGF9 Fusion Protein Expressed in Safflower Stimulates Hair Growth and Wound Healing in Mice
A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.
research Metformin: An Old Medication of New Fashion: Evolving New Molecular Mechanisms and Clinical Implications in Polycystic Ovary Syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research Home-Based Devices in Dermatology: A Systematic Review of Safety and Efficacy
Home-based skin care devices are generally safe and effective for hair removal, promoting hair growth, treating wrinkles and acne, but results for psoriasis treatment are mixed.