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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

PGD2 stops hair growth and is higher in bald men with AGA.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Sebocytes play a key role in controlling androgen levels in human skin.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Researchers created human hair follicles using a new method that could help treat hair loss.

Special fiber materials boost the healing properties of certain stem cells.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Minoxidil sulfate stimulates hair growth.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Minoxidil boosts hair growth by increasing cell production and survival.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Dextran sulfate was found to be toxic and ineffective for treating HIV.