This study found that Botox® was most effective at a 25 U/ml concentration, while Dysport® and Neurobloc® were optimal at 100 U/ml for producing anhidrotic areas after injections.
Botulinum toxin-A may increase hair growth and reduce hair loss in men with baldness, and injecting near blood vessels can improve pain relief and last longer.
May 2018 in “Journal of Sun Yat-sen University” This study found that local injections of botulinum toxin A improved hair density in male patients with androgenetic alopecia over a 6-month period, showing similar effectiveness to the control group.
12 citations
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January 2016 in “Skin appendage disorders” This study reports that women receiving periodic injections of botulinum toxin type A for forehead wrinkles may experience frontal alopecia, with progressive hairline recession observed in the cases studied.
December 2024 in “PubMed” 26 citations
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July 2005 in “Optometry and vision science” This case report documents unilateral madarosis and facial alopecia as potential adverse effects of botulinum A toxin injections in a patient treated for left oromandibular dystonia.
1 citations
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September 2021 in “Skin appendage disorders” This systematic review of five studies found that intradermal and intramuscular botulinum toxin injections showed promising hair growth outcomes for men with androgenic alopecia, but emphasizes caution due to a lack of control groups and small sample sizes.
August 2023 in “Journal of Cosmetic Dermatology” In this study, injecting two different concentrations of botulinum toxin A was found to be safe and effective for treating androgenetic alopecia in Egyptian men and women, with improvements in hair grade and vellus hair density observed over six months.
1 citations
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August 2022 in “International journal of women’s dermatology” This case report suggests that intradermal botulinum toxin type A may alleviate pruritus and reduce papules in Fox-Fordyce disease, improving quality of life without serious adverse effects for at least six months.
1 citations
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September 2021 in “Dermatologic Therapy” The researchers reported that intralesional botulinum toxin A effectively alleviated pain associated with cutaneous leiomyomas in a patient with hereditary leiomyomatosis and renal cell cancer syndrome, with repeated treatments every three months maintaining pain relief over 1.5 years.
September 2025 in “Chinese Journal of Plastic and Reconstructive Surgery” This review reports that while botulinum toxin shows potential mechanisms for treating androgenetic alopecia, recent high-quality trials found no significant hair density improvement compared to placebo, indicating it can't yet replace traditional treatments.
August 2024 in “Archives of Dermatological Research” This study found that in male patients with androgenetic alopecia, combining botulinum toxin type A with 5% Minoxidil significantly improved hair growth, patient satisfaction, and quality of life over six months, compared to using Minoxidil alone, without causing adverse effects.
January 2018 in “프로그램북(구 초록집)” In this study, intradermal injection of botulinum toxin type A significantly increased hair count and improved physician-assessed hair condition in men with male pattern baldness after 24 weeks, with no serious adverse events reported beyond temporary local pain and redness.
April 2016 in “Journal of Investigative Dermatology” This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.
52 citations
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January 2023 in “Toxins” This narrative review discusses expert consensus on the optimal use of botulinum toxin injections for cosmetic applications in facial and oral-maxillofacial areas across Asian and Caucasian populations, highlighting injection techniques, effective doses, historical context, and potential complications.
Botulinum toxin injections can reduce hair loss and stimulate new hair growth in some men with male pattern baldness.
79 citations
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January 1999 in “Dermatologic surgery” This review discusses various dermatologic treatments for periorbital skin rejuvenation but reports no new clinical results; it highlights the importance of patient selection and aging severity in choosing appropriate therapies.
April 2023 in “IntechOpen eBooks” This review discusses neuropathic pruritus, detailing its clinical presentations and management strategies, but reports no new clinical results.
51 citations
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February 2006 in “Clinics in Dermatology” This review discusses the physiological changes in the female body during pregnancy, relating them to hormonal shifts, and comments on treatment considerations, but it presents no new research findings.
20 citations
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December 2016 in “American Journal of Clinical Dermatology” This review discusses the most popular non-surgical cosmetic procedures for men and highlights the importance of considering sex-specific factors for optimal treatment, but reports no new clinical results.
7 citations
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April 2014 in “Facial Plastic Surgery Clinics of North America” This review covers complications of neck lift surgery, their causes, ways to reduce them, and management strategies, without offering new clinical findings.
3 citations
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April 2022 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses evidence-based complementary strategies for enhancing hair regrowth after post-COVID-19 telogen effluvium and reports no new clinical results.
2 citations
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October 2024 in “PubMed” The authors reviewed nine studies on various dermatological procedures for treating Seborrheic Dermatitis, noting significant efficacy in small cohorts with high patient satisfaction, but highlighted the need for further research to address challenges like cost, variable effectiveness, and long-term safety.
September 2024 in “Journal of Drugs in Dermatology” This review found that various dermatological procedures for Seborrheic Dermatitis, such as phototherapy and laser treatments, showed significant efficacy in small cohorts with high patient satisfaction, but highlighted the need for further research to standardize protocols and evaluate long-term outcomes.
9 citations
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January 2023 in “Indian Dermatology Online Journal” This review discusses the use of aesthetic treatments for medical purposes and their therapeutic potential but provides no new clinical results.
7 citations
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January 1998 This article reviews various cosmetic procedures like botulinum A exotoxin and chemical peels for aesthetic enhancement but reports no new clinical findings, emphasizing existing methods.
August 2023 in “Journal of Dermatological Treatment” This systematic review concluded that mesotherapy shows potential for improving hair growth outcomes, yet lacks standardized regimens and requires further large-scale trials to establish its efficacy and safe use.
June 2009 in “マテリアルインテグレ-ション” This review discusses the most popular non-surgical cosmetic procedures pursued by men and highlights the importance of sex-specific considerations in treating male cosmetic patients; it reports no new clinical results.
9 citations
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September 2015 in “Medical Clinics of North America” This article reviews common dermatologic procedures, focusing on skin biopsy techniques, with no new clinical results reported.
Botulinum toxin-A injections in the scalp can reduce hair loss and promote new hair growth in men with certain types of baldness.