26 citations,
August 1971 in “Journal of Morphology” Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.
22 citations,
May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
4 citations,
August 2023 in “Nature Communications” Mouse zigzag hair bends form due to a 3-day cycle of changes in hair progenitors and their environment.
3 citations,
October 2022 in “PloS one” Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
2 citations,
August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
April 2024 in “Research Square (Research Square)” 16-MHA can restore the barrier and moisture of damaged hair, making it similar to undamaged hair.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Different fish use the same genes to regrow teeth.
Researchers developed a new device that improves non-incision hair transplant efficiency.
271 citations,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
116 citations,
May 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
72 citations,
November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
51 citations,
May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
28 citations,
October 2004 in “Differentiation” A gene deletion causes the "hairless" trait in Iffa Credo rats.
14 citations,
May 2019 in “Human gene therapy” MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
January 2024 in “Polski Merkuriusz Lekarski” Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.
September 2023 in “Frontiers in cell and developmental biology” Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
98 citations,
December 2003 in “The FASEB Journal” Thymosin β4 promotes hair growth by activating stem cells in hair follicles.
13 citations,
August 2020 in “Frontiers in Cell and Developmental Biology” Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.
1 citations,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Primary cilia affect the size and oil production of eye glands but not the oil's makeup.
62 citations,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
8 citations,
February 2015 in “Cellular immunology” Deleting Snai2 and Snai3 causes fatal autoimmunity.
2 citations,
October 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
September 2017 in “Journal of Investigative Dermatology” The research concluded that hyaluronic acid affects the formation and growth of hair follicle-like structures in a lab setting.
1 citations,
January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
5 citations,
September 2022 in “Research Square (Research Square)” CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
5 citations,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.