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This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.

This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.

This study developed a mouse model for radiation cystitis that mimics human pathology and found that radiation exposure leads to increased urinary frequency and long-term weakening of urothelial integrity.

This review discusses follicular and scarring disorders in skin of color and highlights the need for patient education and tailored therapeutic strategies, but does not report new clinical findings.

This study found that dermatology leads in performing office-based cosmetic procedures compared to other specialties, with dermatologists and plastic surgeons having the most experience per physician.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

This study reports that eccrine sweat glands in mice predominantly develop on the footpads, offering a reference for skin research involving genetically engineered mice.

This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.

This article discusses intraoperative floppy iris syndrome during cataract surgery and highlights the importance of awareness and preoperative documentation of its risk factors, emphasizing a multidisciplinary approach to management.

This review examines how male facial anatomy and behavior contribute to sexual dimorphism in facial aging, pointing to factors that accelerate aging in men but presents no new clinical results.

This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.

In this systematic review, tSVF-based therapy demonstrated favorable outcomes for various pathologies, including aged skin and osteoarthritis, with low incidence of adverse events, while highlighting the need for further research into optimal protocols and mechanisms of action.

This review examines mesotherapy for local fat reduction, detailing its mechanisms, safety concerns, and the need for research toward FDA-approved uses, but reports no new clinical findings.

This commentary reviews the controversial use of mesotherapy for androgenetic alopecia and emphasizes the need for documented evidence, without reporting new clinical results.

This article discusses the unique considerations for cosmetic surgery on the Asian male face and reports no new research findings; it emphasizes different psychological approaches and surgical techniques.

This study identified upregulation of genes linked to fibroproliferative disorders, such as platelet-derived growth factor and collagen genes, in patients with central centrifugal cicatricial alopecia, suggesting potential therapeutic targets.

This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.

This article reviews the principles and practical considerations of laser and light-based hair removal techniques, but it does not report new clinical findings.

This review discusses the dermatology of nonhuman primates and emphasizes the need for a cohesive approach to study and report their dermatologic diseases, without assuming similarities to human or other veterinary conditions.

This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.

This review discusses treatment options for tics in Gilles de la Tourette syndrome, highlighting existing therapies and potential future advancements, but reports no new clinical findings.

This article reviews the pathophysiology, diagnosis, and treatment of female pattern hair loss, highlighting the importance of early medical intervention to arrest hair loss progression, but reports no new clinical results.

This review explores potential new roles for Merkel cells, including involvement in magnetoreception, fingerprint formation, and transmitting environmental information, but reports no experimental results.

This consensus concluded that oral isotretinoin is highly effective for treating acne and some off-label conditions, with common adverse events being manageable and rare serious risks not contraindicating use.

This review discusses the role of steroid sulfatase in steroid hormone metabolism and highlights the need for more research on its expression and regulation, especially regarding hormone-dependent tumors.

This study found that dermatology leads in performing office-based cosmetic procedures compared to other specialties, with a focus on white, female patients aged 40 to 59.

This review explores the mechanisms, techniques, and clinical applications of microneedling, highlighting its advantages and challenges in skin rejuvenation, and discusses future innovations in the field as it continues to evolve.

This review discusses skin diseases in transgender patients receiving gender-affirming hormone therapy and procedures, highlighting unique conditions and the underdiagnosis that affects their quality of life and mental health.

This article proposes a new classification, the Obsessive-Compulsive Insight Continuum, to help dermatologists better understand and diagnose skin disorders with obsessive-compulsive features.

This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.