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Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Vitamin D receptor is crucial for bone health and mineral metabolism.

Advanced human skin models improve drug development and could replace animal testing.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.

A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Stem cell therapy may help treat tough hair loss cases.

Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.

EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.

Platelet-Rich Plasma (PRP) shows promise for treating various skin conditions, but more research is needed to standardize its use.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Mice with CBS deficiency are healthier on a low-methionine diet.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

VDR regulation varies by tissue and is crucial for its biological functions.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.

Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.