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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Fat cells help recruit healing cells and build skin structure during wound healing.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Different types of skin cells play specific roles in development, healing, and cancer.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.