research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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480-510 / 1000+ results research Epidermal Stem Cells in Orthopedic Regenerative Medicine
Epidermal stem cells show promise for treating orthopedic injuries and diseases.
research Intractable Diffuse Alopecia Caused by Multifactorial Side-Effects in Treatment of Acute Lymphocytic Leukemia: Connection to Iatrogenic Failure of Estrogen Secretion
The patient's long-term hair loss was caused by leukemia treatments and low estrogen levels, worsened by her genetic tendency for hair loss.
research Basal Cell Carcinomas of the Scalp: Review of 77 Patients with 81 Tumors
The review found that basal cell carcinomas on the scalp are not more aggressive than those in other locations.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.
research Secretome of Mesenchymal Stromal Cells as a Possible Innovative Therapeutic Tool in Facial Nerve Injury Treatment
The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.
research Acute Hepatitis and Pancytopenia in a Child With Chronic Abuse of Senna
A child's chronic use of Senna caused liver damage and a severe decrease in blood cells, but improved after stopping Senna and getting treatment.
research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products
Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
research Mesenchymal Stem Cells for the Treatment of Skin Diseases
Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
research A New Species of Aplodontopus (Acari: Astigmata: Chortoglyphidae) from the Yellow-Bellied Marmot, Marmota Flaviventris (Rodentia: Sciuridae) in Eastern Washington, USA, with Observations on Its Pathology
Researchers found a new mite species causing severe hair loss and skin problems in yellow-bellied marmots.
research A Case of Systemic Mastocytosis: An Ultrastructural and Immunohistochemical Study of Dermal Mast Cells in Relation to Activation of the Epidermal Melanin Unit
Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.
research Sequential Estrogen-Progestin Addition to Gonadotropin-Releasing Hormone Agonist Suppression for the Chronic Treatment of Ovarian Hyperandrogenism: A Pilot Study
The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
research Exploring Hormone Therapy Effects on Reproduction and Health in Transgender Individuals
Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
research Appraisal of Paclitaxel Pros and Cons in Cancer Management and Drug Repurposing Prospects
Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.
research Effect of Lifestyle Pattern and Cultural Practices on Vitamin D Status of Muslim Women in Coimbatore City
Muslim women in Coimbatore with limited sunlight exposure due to cultural dress and lifestyle have low vitamin D levels.
research Single-Cell Analysis Identifies Heterogeneity of Fibroblasts and Myeloid-Derived Adipocytes in Regenerating Mouse Skin Wounds
Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
research Regeneration, Wound Healing, and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
research Clinical Evaluation of Women Presenting with Low Libido and Determination of Whether Androgen Therapy Might Be Appropriate
Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
research Stable Isotope Analyses of Carbon and Nitrogen in Hair Keratin of Suspected Man-Eating Wolves from the 1880s
The wolves suspected of man-eating in the 1880s likely ate very little human flesh and mostly consumed a diet similar to herbivores and omnivores.
research Investigating the Use of Autologous Stem Cell Therapy in the Treatment of Androgenetic Alopecia
Autologous stem cell therapy may effectively increase hair density in Androgenetic Alopecia.
research A Review of Autologous Stem Cell-Based Therapy as a Potential Treatment Option for Androgenetic Alopecia
Stem cell therapy shows promise for treating hair loss.
research The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration
Mesenchymal stem cells show promise for effective skin repair and regeneration.
research Autologous Stem Cell-Derived Therapies for Androgenetic Alopecia: A Systematic Review of Randomized Control Trials on Efficacy, Safety, and Outcomes
Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
research Ginsenosides in Panax Ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation
Panax ginseng extract helps human hair grow by encouraging growth phase transition and cell proliferation while reducing certain protein expression.
research AP Collagen Peptides Improve Hair Growth and Quality by Promoting Human Hair Cell Proliferation and Keratin Synthesis
AP collagen peptides may help hair grow better and become stronger.
research Alopecia With Vitamin D-Dependent Rickets Type 2A: A Case Report
A child with a rare vitamin D-resistant condition improved with treatment.
research Effects of Androgen Treatment on Growth in Patients with 5-Alpha-Reductase Type 2 Deficiency
Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.
research Complex Extract of Polygonatum Sibiricum and Nelumbinis Semen Improves Menopause Symptoms via Regulation of Estrogen Receptor Beta in an Ovariectomized Rat Model
A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.