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Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

The document explains how male reproductive hormones work and affect the body.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Lower SHBG levels may increase the risk of PCOS.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.

miR-29 is a key factor that accelerates aging.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

New therapies are being developed that target integrin pathways to treat various diseases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Vitamin D is important for skin health and can affect various skin diseases.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Higher vitamin D levels are linked to higher iron levels in Korean women without metabolic syndrome, but not in those with it.

Eclipta prostrata is a medicinal plant that helps treat diseases, protects the liver and nerves, and promotes hair growth.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.