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New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.

More research is needed to understand how testosterone is maintained in adult males.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Women with PCOS have higher risks of heart disease, type 2 diabetes, and endometrial cancer.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Wearing headcovers doesn't affect male-pattern hair loss severity.

Mesotherapy might be a useful addition to dental surgery to reduce drug use and side effects, but more research is needed.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

The combination therapy was effective and well-tolerated, especially in young patients.

Alternating treatment with two drugs could help cells in a rapid aging disease.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.