24 citations,
August 2017 in “Prostaglandins & Other Lipid Mediators” CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
18 citations,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
21 citations,
June 1990 in “British Journal of Dermatology” Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
10 citations,
August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
7 citations,
September 2023 in “Cancer Treatment Reviews” Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.
1 citations,
January 2020 in “Bioscience Reports” Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
400 citations,
January 2014 in “British Journal of Sports Medicine” The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.
15 citations,
October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
54 citations,
June 2018 in “Nutrients” Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.
19 citations,
May 2020 in “American journal of men's health” Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
4 citations,
December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
October 2023 in “Naunyn-Schmiedeberg's Archives of Pharmacology” Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
September 2023 in “Physiology and Pharmacology” Glucocorticoids can cause various health issues, but some treatments may help reduce these effects.
40 citations,
September 2007 in “Bone marrow transplantation” Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.
July 2023 in “The Journal of Clinical Endocrinology and Metabolism” Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
1 citations,
January 2009 in “Elsevier eBooks” Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.
16 citations,
January 2006 in “The Aging Male” Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
441 citations,
May 2008 in “British Journal of Pharmacology” Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
103 citations,
June 2006 in “British journal of sports medicine” The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
51 citations,
January 2012 in “Annals of dermatology/Annals of Dermatology” A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
33 citations,
April 2011 in “Journal of Veterinary Internal Medicine” Long-term fluticasone treatment does not harm the immune system in horses with heaves.
14 citations,
November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.
11 citations,
January 2017 in “Biochemical and biophysical research communications” 1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
11 citations,
January 2011 in “Turkish Journal of Medical Sciences” Low iron levels are a significant risk factor for hair loss, while high vitamin D levels might be a response to hair loss, not a cause.
6 citations,
March 2015 in “Journal of Endocrinological Investigation” Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.
2 citations,
September 2022 in “Bioscientia medicina” Topical vitamin D is effective in treating vitiligo with few side effects.
2 citations,
June 2022 in “Scientific reports” Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
1 citations,
August 2015 in “Current Sexual Health Reports” 5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
December 2023 in “JCEM case reports” A new gene variant causes glucocorticoid resistance in a mother and son.