research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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research Intractable Diffuse Alopecia Caused by Multifactorial Side-Effects in Treatment of Acute Lymphocytic Leukemia: Connection to Iatrogenic Failure of Estrogen Secretion
The patient's long-term hair loss was caused by leukemia treatments and low estrogen levels, worsened by her genetic tendency for hair loss.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.
research Mesenchymal Stem Cells for the Treatment of Skin Diseases
Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
research Acute Hepatitis and Pancytopenia in a Child With Chronic Abuse of Senna
A child's chronic use of Senna caused liver damage and a severe decrease in blood cells, but improved after stopping Senna and getting treatment.
research A New Species of Aplodontopus (Acari: Astigmata: Chortoglyphidae) from the Yellow-Bellied Marmot, Marmota Flaviventris (Rodentia: Sciuridae) in Eastern Washington, USA, with Observations on Its Pathology
Researchers found a new mite species causing severe hair loss and skin problems in yellow-bellied marmots.
research Appraisal of Paclitaxel Pros and Cons in Cancer Management and Drug Repurposing Prospects
Paclitaxel is an effective cancer drug with side effects and potential new uses beyond cancer.
research Single-Cell Analysis Identifies Heterogeneity of Fibroblasts and Myeloid-Derived Adipocytes in Regenerating Mouse Skin Wounds
Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
research Investigating the Use of Autologous Stem Cell Therapy in the Treatment of Androgenetic Alopecia
Autologous stem cell therapy may effectively increase hair density in Androgenetic Alopecia.
research A Review of Autologous Stem Cell-Based Therapy as a Potential Treatment Option for Androgenetic Alopecia
Stem cell therapy shows promise for treating hair loss.
research The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration
Mesenchymal stem cells show promise for effective skin repair and regeneration.
research Advances in Hair Restoration: Wnt/Beta-Catenin Pathway and Stem Cell-Based Therapies
New treatments for hair loss could involve using stem cells and a process called the Wnt/beta-catenin pathway to stimulate hair growth.
research Scalp Biopsy Identifies Systemic Amyloidosis Presenting as Isolated Telogen Effluvium: A Case Report
A scalp biopsy revealed systemic amyloidosis in a woman who initially seemed to have a common hair loss condition.
research Hypercalcemia-Induced Altered Mental Status as the Primary Manifestation of Classic Hodgkin Lymphoma
An 87-year-old man showed unusual signs of Hodgkin lymphoma, primarily high calcium levels, which improved after treatment and revealed the disease.
research Finasteride Promotes Worsening of the Cardiac Deleterious Effects of Nandrolone Decanoate and Protects Against Genotoxic and Cytotoxic Damage
Finasteride worsens heart damage but reduces cell toxicity caused by nandrolone decanoate.
research Stress-Induced Chemokine Production by Hair Follicles Recruits Dendritic Cells to Sites of Minor Trauma
Hair follicles help attract immune cells to minor skin injuries.
research 8th Postgraduate Seminar in Pediatric Dermatology
Experts discussed treatments for skin conditions in children, emphasizing hydration, cautious medication use, and early intervention for infections.
research Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review
Stem cell treatments show promise for hair loss but need more research.
research White Monkey Syndrome in Infant Baboons (Papio Species)
Infant baboons suffered from zinc poisoning due to poor cage conditions.
research Should We Consider Alternative Therapies to Operative Hysteroscopy for the Treatment of Asherman Syndrome?
Operative hysteroscopy is still the main treatment for Asherman syndrome, but more research is needed on post-surgery methods.
research Growth Factors and Microneedling in Alopecia Areata: A Narrative Review
Using growth factors and microneedling shows promise for hair regrowth in Alopecia Areata, but more research is needed.
research Stem Cell Niches in Mammals
Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
research Injectable Silk Nanofiber Hydrogels as Stem Cell Carriers to Accelerate Wound Healing
Silk nanofiber hydrogels help stem cells heal wounds faster and improve skin regeneration.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Adipose-Derived Stromal Cells in Regenerative Medicine: A Review
Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
research Stem Cells Supporting Other Stem Cells
Stem cells can help other stem cells by producing supportive factors.
research Targeting Adult Mesenchymal Stem Cells Plasticity for Tissue Regeneration
Adult mesenchymal stem cells can help regenerate tissues and are promising for healing bones, wounds, and hair follicles.
research Permanent Alopecia Post-Chemotherapy with Favorable Response to Topical Minoxidil
Topical minoxidil may help regrow hair after permanent hair loss from chemotherapy.
research Hair Today, Gone Tomorrow: Potential of Tofacitinib and Ruxolitinib in Treating Hair Loss
Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.