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The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Platelet concentrates are useful for tissue repair in medicine and dentistry, with L-PRF showing promising results in various treatments.

Scientists can control how skin stem cells divide by using different treatments.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Whale genes show changes that help them live in water, like less hair and better flippers.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

ILK is essential for skin development, pigmentation, and healing.

Testosterone is crucial for development, growth, and various body functions in mammals.

RCS-01 therapy is safe and may improve skin structure by affecting gene expression.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.