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A 3-year-old girl developed scurvy symptoms that improved with vitamin C but relapsed when supplementation stopped.

Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.

CD133+ progenitor cells have therapeutic potential for diabetic ulcers and heart attack recovery, with manageable risks.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

A fragment of human type XVII collagen shows great potential for skin health and wound healing.

Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Keratin from hair and wool is used in medical materials for healing and drug delivery.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

New effective scar treatments are urgently needed due to the current options' limited success.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

μ-opiate receptors in skin cells may affect skin health and healing.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Scientists created stem cells that can grow hair and skin.

Skin fat helps with body temperature control and has other active roles in health.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.