13 citations
,
February 2018 in “Plastic and Reconstructive Surgery” The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
8 citations
,
October 2005 in “Otolaryngologic Clinics of North America” This article discusses the mechanisms and prevention of aging, particularly in facial rejuvenation, but reports no new experimental findings.
7 citations
,
September 2024 in “BMC Genomics” In this study, whole-genome sequencing of Lanping black-boned sheep identified ERBB4 and ROR1 genes as potentially important in their distinctive hyperpigmentation, enhancing understanding of their genetic evolution from Lanping normal sheep.
7 citations
,
August 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Scalp-to-scalp skin grafts quickly heal and hide well under regrown hair, making them good for repairing large scalp defects.
5 citations
,
September 1994 in “The Journal of Dermatologic Surgery and Oncology” This article discusses extensive scalp lifting for male-pattern alopecia and emphasizes the need for precise surgical techniques and understanding to minimize complications, but reports no new clinical results.
3 citations
,
July 2021 in “Life science alliance” This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.
3 citations
,
July 1987 in “Dermatologic Clinics” This article discusses scalp reductions for male-pattern baldness and reports potential challenges, such as stretch-back and scar-related styling issues, without providing new clinical results.
2 citations
,
May 2019 in “Advances in wound care” In this study, nondermal-derived CD34+ cells from adult peripheral blood were found to enhance wound healing and contribute to hair follicle neogenesis and skin regeneration.
January 2026 in “Forum Dermatologicum” This study observed that 2.5% of patients with mycosis fungoides or Szary syndrome experienced alopecia, predominantly within skin lesions, with scalp metastases from other cancers also potentially causing hair loss, highlighting the diagnostic value of trichoscopy in differentiating alopecia types.
July 2019 in “Acta Scientiae Veterinariae” This case report describes a Canadian Husky dog with sertolioma that exhibited dermatological symptoms and aggressive behavior, both of which improved significantly after surgery.
April 2019 in “Journal of Investigative Dermatology” This study found that DPP4 is significantly involved in matrix deposition and fibrosis in human skin fibroblasts, although the exact functions of DPP4 remain unclear.
April 2019 in “Journal of Investigative Dermatology” This study found that mice lacking REDD1 experienced an expansion of dermal white adipose tissue through both hypertrophy and hyperplasia, suggesting a potential therapeutic target for skin adipogenesis regulation.
April 2019 in “Journal of Investigative Dermatology” This study in mice found that fractional photothermolysis can improve dermal scar formation by promoting slow, organized collagen regeneration with minimal myofibroblast activation.
April 2019 in “Journal of Investigative Dermatology” This study found that CYP11A1-derived vitamin D3 analogs inhibit fibroblast proliferation and decrease collagen production through VDR expression, showing potential antifibrotic and antiproliferative activity in human dermal fibroblasts.
April 2019 in “Journal of Investigative Dermatology” This study found that BRG1 is crucial for keratinocyte migration during skin wound healing, as its suppression impairs wound closure by inhibiting migration without affecting cell proliferation or apoptosis.
July 2016 in “American Journal of Dermatopathology” The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.
This section presents 70 multiple choice questions designed for haematology specialist trainees, covering complex clinical cases and their likely diagnoses, adverse events, and management advice.
This article presents a collection of 70 multiple choice questions designed to assist haematology and core medical trainees with diagnostic and management skills, but it provides no new clinical findings.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
This case report describes an ulcerated lesion in the oral cavity of an 85-year-old man that has not responded to various treatments and remains without a conclusive diagnosis.
August 2004 in “Journal of the American College of Surgeons” Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
September 2001 in “Dermatologic Surgery” This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.
480 citations
,
August 2014 in “Nature Biotechnology” This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.
1 citations
,
May 2023 in “Curēus” In this case report, a rare pilar cyst was found in the left temporal region of a 75-year-old male, highlighting the potential for such cysts to mimic temporal space infections and complicate treatment plans.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
326 citations
,
February 2009 in “The American journal of pathology” This review discusses the role of Lgr5 as a marker for identifying adult stem cells, particularly in the intestine and hair follicles, and reports no clinical results.
291 citations
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April 2010 in “Gastroenterology” This study identified Lgr5 and Lgr6 as receptors expressed by small populations of stem cells in various adult organs, with Lgr5+ve cells forming long-lived organoids in certain mouse models.
211 citations
,
November 2018 in “Nature Cell Biology” This article discusses the coordinated roles of different epidermal stem cells and other cell types in the skin's wound healing process and reports no new experimental results.
204 citations
,
October 1999 in “EMBO journal” This study found that overexpression of activin in transgenic mice led to enhanced granulation tissue formation after skin injury due to changes in keratinocyte proliferation and differentiation.
182 citations
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June 2017 in “Biomaterials” This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.