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Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

Fresh plasma transfusions did not help treat Leiner disease in an infant.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Chemotherapy and bone marrow transplant can cause permanent hair loss.

Blocking a specific protein signal can make hair grow on mouse nipples.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Vogt-Koyanagi-Harada disease can develop during interferon therapy for chronic hepatitis C.

Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.

Chemotherapy caused the patient's hair to have alternating thick and thin segments.

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.

Low vitamin D3 is not linked to different levels of thyroid hormones in people with autoimmune thyroid disease.

Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Testosterone therapy increases bone density in older men with low testosterone levels.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Bone marrow and umbilical cord stem cells can help grow new hair.

GLI2 increases follistatin production in human skin cells.