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A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Lower SHBG levels may increase the risk of PCOS.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

A new gene, JMJD1C, may affect testosterone levels in men.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

SHBG may be a useful early indicator and treatment target for PCOS.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Premature hair graying in young men is linked to family history, obesity, and smoking.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.